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genotype tissue expression gtex data  (Human Protein Atlas)

 
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    Human Protein Atlas genotype tissue expression gtex data
    The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal <t>tissues.</t> <t>Genotype</t> Tissue Expression <t>(GTEx)</t> data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.
    Genotype Tissue Expression Gtex Data, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/genotype+tissue+expression+gtex+data/pmc12359157-89-0-16?v=Human+Protein+Atlas
    Average 86 stars, based on 1 article reviews
    genotype tissue expression gtex data - by Bioz Stars, 2026-07
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    1) Product Images from "Exploring CISD1 as a multifaceted biomarker in cancer: Implications for diagnosis, prognosis, and immunotherapeutic response"

    Article Title: Exploring CISD1 as a multifaceted biomarker in cancer: Implications for diagnosis, prognosis, and immunotherapeutic response

    Journal: Genes & Diseases

    doi: 10.1016/j.gendis.2025.101677

    The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.
    Figure Legend Snippet: The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.

    Techniques Used: Expressing, Quantitative Proteomics



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    The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal <t>tissues.</t> <t>Genotype</t> Tissue Expression <t>(GTEx)</t> data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.
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    The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal <t>tissues.</t> <t>Genotype</t> Tissue Expression <t>(GTEx)</t> data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.
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    Pan‐cancer expression of XPO1. (A) XPO1 expression in tumor and normal tissues in pan‐cancer data of the <t>Cancer</t> <t>Genome</t> <t>Atlas</t> <t>(TCGA)</t> and GTEx. (B) XPO1 expression in tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. (C) XPO1 expression in paired tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001. CHOL, cholangiocarcinoma; GTEx, genotype‐tissue expression; LIHC, liver hepatocellular carcinoma; PAAD, pancreatic adenocarcinoma; TCGA, the cancer genome atlas; XPO1, exportin‐1.
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    Pan‐cancer expression of XPO1. (A) XPO1 expression in tumor and normal tissues in pan‐cancer data of the <t>Cancer</t> <t>Genome</t> <t>Atlas</t> <t>(TCGA)</t> and GTEx. (B) XPO1 expression in tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. (C) XPO1 expression in paired tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001. CHOL, cholangiocarcinoma; GTEx, genotype‐tissue expression; LIHC, liver hepatocellular carcinoma; PAAD, pancreatic adenocarcinoma; TCGA, the cancer genome atlas; XPO1, exportin‐1.
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    Image Search Results


    The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.

    Journal: Genes & Diseases

    Article Title: Exploring CISD1 as a multifaceted biomarker in cancer: Implications for diagnosis, prognosis, and immunotherapeutic response

    doi: 10.1016/j.gendis.2025.101677

    Figure Lengend Snippet: The mRNA expression levels of CISD1 in human pan-cancer. (A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.

    Article Snippet: Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues.

    Techniques: Expressing, Quantitative Proteomics

    Pan‐cancer expression of XPO1. (A) XPO1 expression in tumor and normal tissues in pan‐cancer data of the Cancer Genome Atlas (TCGA) and GTEx. (B) XPO1 expression in tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. (C) XPO1 expression in paired tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001. CHOL, cholangiocarcinoma; GTEx, genotype‐tissue expression; LIHC, liver hepatocellular carcinoma; PAAD, pancreatic adenocarcinoma; TCGA, the cancer genome atlas; XPO1, exportin‐1.

    Journal: Cancer Medicine

    Article Title: Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation

    doi: 10.1002/cam4.5322

    Figure Lengend Snippet: Pan‐cancer expression of XPO1. (A) XPO1 expression in tumor and normal tissues in pan‐cancer data of the Cancer Genome Atlas (TCGA) and GTEx. (B) XPO1 expression in tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. (C) XPO1 expression in paired tumor and normal tissues in CHOL, LIHC, and PAAD from TCGA. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001. CHOL, cholangiocarcinoma; GTEx, genotype‐tissue expression; LIHC, liver hepatocellular carcinoma; PAAD, pancreatic adenocarcinoma; TCGA, the cancer genome atlas; XPO1, exportin‐1.

    Article Snippet: XPO1 expression profiles and TCGA and Genotype‐Tissue Expression (GTEx) clinical pan‐cancer data were downloaded from the University of California, Santa Cruz (UCSC) Xena database ( https://xenabrowser.net/datapages/ ).

    Techniques: Expressing

    Association between high XPO1 expression and tumor prognosis in patients. (A–F) The correlation between XPO1 expression and the prognosis of CHOL, LIHC, and PAAD was analyzed using TCGA. (G) The correlation between XPO1 expression and the prognosis of CHOL was analyzed using the GEO database. (H) The correlation between XPO1 expression and “N stage” in CHOL. (I) The correlation between XPO1 expression and “Vascular invasion” in CHOL. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. CHOL, cholangiocarcinoma; LIHC, liver hepatocellular carcinoma; PAAD, pancreatic adenocarcinoma; TCGA, the cancer genome atlas; XPO1, exportin‐1.

    Journal: Cancer Medicine

    Article Title: Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation

    doi: 10.1002/cam4.5322

    Figure Lengend Snippet: Association between high XPO1 expression and tumor prognosis in patients. (A–F) The correlation between XPO1 expression and the prognosis of CHOL, LIHC, and PAAD was analyzed using TCGA. (G) The correlation between XPO1 expression and the prognosis of CHOL was analyzed using the GEO database. (H) The correlation between XPO1 expression and “N stage” in CHOL. (I) The correlation between XPO1 expression and “Vascular invasion” in CHOL. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. CHOL, cholangiocarcinoma; LIHC, liver hepatocellular carcinoma; PAAD, pancreatic adenocarcinoma; TCGA, the cancer genome atlas; XPO1, exportin‐1.

    Article Snippet: XPO1 expression profiles and TCGA and Genotype‐Tissue Expression (GTEx) clinical pan‐cancer data were downloaded from the University of California, Santa Cruz (UCSC) Xena database ( https://xenabrowser.net/datapages/ ).

    Techniques: Expressing

    Correlation and enrichment analyses in CHOL. (A) The top 50 genes positively correlated with XPO1in a heat map (ranked according to correlation) from TCGA. (B–F) Significant Gene Ontology terms of the top 500 genes most positively associated with XPO1, including biological processes (C), cell component (D), molecular function (E), and KEGG (F). CHOL, cholangiocarcinoma; KEGG, Kyoto encyclopedia of genes and genomes; TCGA, the cancer genome atlas; XPO1, exportin‐1.

    Journal: Cancer Medicine

    Article Title: Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation

    doi: 10.1002/cam4.5322

    Figure Lengend Snippet: Correlation and enrichment analyses in CHOL. (A) The top 50 genes positively correlated with XPO1in a heat map (ranked according to correlation) from TCGA. (B–F) Significant Gene Ontology terms of the top 500 genes most positively associated with XPO1, including biological processes (C), cell component (D), molecular function (E), and KEGG (F). CHOL, cholangiocarcinoma; KEGG, Kyoto encyclopedia of genes and genomes; TCGA, the cancer genome atlas; XPO1, exportin‐1.

    Article Snippet: XPO1 expression profiles and TCGA and Genotype‐Tissue Expression (GTEx) clinical pan‐cancer data were downloaded from the University of California, Santa Cruz (UCSC) Xena database ( https://xenabrowser.net/datapages/ ).

    Techniques:

    Effect of BIRC6 on p53. (A) Correlation between exportin‐1 (XPO1) and BIRC6 from TCGA. (B) Western blot of p53 and BIRC6 under KPT‐330 treatment. (C) Western blot of p53 and BIRC6 under KPT‐330 treatment and overexpression of BIRC6. (D) Cell proliferation of RBE and 9810 under KPT‐330 treatment and overexpression of BIRC6. (E) Western blot of PI3K/AKT pathway and BIRC6 under KPT‐330 treatment and 740 Y‐P. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

    Journal: Cancer Medicine

    Article Title: Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation

    doi: 10.1002/cam4.5322

    Figure Lengend Snippet: Effect of BIRC6 on p53. (A) Correlation between exportin‐1 (XPO1) and BIRC6 from TCGA. (B) Western blot of p53 and BIRC6 under KPT‐330 treatment. (C) Western blot of p53 and BIRC6 under KPT‐330 treatment and overexpression of BIRC6. (D) Cell proliferation of RBE and 9810 under KPT‐330 treatment and overexpression of BIRC6. (E) Western blot of PI3K/AKT pathway and BIRC6 under KPT‐330 treatment and 740 Y‐P. Data were shown as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

    Article Snippet: XPO1 expression profiles and TCGA and Genotype‐Tissue Expression (GTEx) clinical pan‐cancer data were downloaded from the University of California, Santa Cruz (UCSC) Xena database ( https://xenabrowser.net/datapages/ ).

    Techniques: Western Blot, Over Expression